Lacticaseibacillus rhamnosus HF01 fermented yogurt alleviated high-fat diet-induced obesity and hepatic steatosis via the gut microbiota–butyric acid–hepatic lipid metabolism axis

作者：Yue Sun, Xiaolin Liu, Rongchun Wang, Rongmei Liu, Xuepeng Lv, Ying Ma, Qiming Li · 发表于：Food & Function · 年份：2024 · DOI：10.1039/d3fo04985j · 被引用次数：37 · 研究领域：Gut microbiota and health、Diet and metabolism studies、Tryptophan and brain disorders

. These alterations led to an increase of the cecum butyric acid content, which in turn indirectly promoted the activation of the AMPK signaling pathway, subsequently, inhibited fat synthesis, and promoted fatty acid oxidation related gene expression. Therefore, HF01-Y was likely to alleviate hepatic fat and relieve obesity by modulating the gut microbiota-butyric acid-hepatic lipid metabolism axis, ultimately promoting host health.