Discovery of GS-9131: Design, synthesis and optimization of amidate prodrugs of the novel nucleoside phosphonate HIV reverse transcriptase (RT) inhibitor GS-9148

作者：Richard L. Mackman, Adrian S. Ray, Hon C. Hui, Lijun Zhang, Gabriel Birkuš, Constantine G. Boojamra, Manoj C. Desai, Janet L. Douglas, Ying Gao, Deborah Grant, Geneviève Laflamme, Kuei‐Ying Lin, David Y. Markevitch, Ruchika Mishra, Martin J. McDermott, Rowchanak Pakdaman, Oleg V. Petrakovsky, Jennifer E. Vela, Tomáš Cihlář · 发表于：Bioorganic & Medicinal Chemistry · 年份：2010 · DOI：10.1016/j.bmc.2010.03.041 · 被引用次数：59 · 研究领域：HIV Research and Treatment、HIV/AIDS drug development and treatment、Biochemical and Molecular Research