Deborah Grant

机构：Gilead Sciences (United States)

发表论文 15 篇 · 总被引 605 次 · h-index 11

代表论文

• Potent and selective inhibition of gene expression by an antisense heptanucleotide (1996 · Nature Biotechnology · 被引 119)
• Site and Mechanism of Antisense Inhibition by C-5 Propyne Oligonucleotides (1995 · Biochemistry · 被引 96)
• Design and Profiling of GS-9148, a Novel Nucleotide Analog Active against Nucleoside-Resistant Variants of Human Immunodeficiency Virus Type 1, and Its Orally Bioavailable Phosphonoamidate Prodrug, GS-9131 (2007 · Antimicrobial Agents and Chemotherapy · 被引 94)
• Antisense Gene Inhibition by C-5-Substituted Deoxyuridine-Containing Oligodeoxynucleotides (1997 · Biochemistry · 被引 60)
• Discovery of GS-9131: Design, synthesis and optimization of amidate prodrugs of the novel nucleoside phosphonate HIV reverse transcriptase (RT) inhibitor GS-9148 (2010 · Bioorganic & Medicinal Chemistry · 被引 59)
• Synthesis and anti-HIV activity of GS-9148 (2′-Fd4AP), a novel nucleoside phosphonate HIV reverse transcriptase inhibitor (2007 · Bioorganic & Medicinal Chemistry Letters · 被引 58)