Manoj C. Desai

机构：Martinez VA Medical Center, Gilead Sciences (United States)

发表论文 150 篇 · 总被引 4187 次 · h-index 29

代表论文

• Discovery of Ledipasvir (GS-5885): A Potent, Once-Daily Oral NS5A Inhibitor for the Treatment of Hepatitis C Virus Infection (2013 · Journal of Medicinal Chemistry · 被引 293)
• Discovery of an Oral Respiratory Syncytial Virus (RSV) Fusion Inhibitor (GS-5806) and Clinical Proof of Concept in a Human RSV Challenge Study (2015 · Journal of Medicinal Chemistry · 被引 128)
• Discovery of Dihydrobenzoxazepinone (GS-6615) Late Sodium Current Inhibitor (Late I Na i), a Phase II Agent with Demonstrated Preclinical Anti-Ischemic and Antiarrhythmic Properties (2016 · Journal of Medicinal Chemistry · 被引 36)
• Structure–activity relationships of diamine inhibitors of cytochrome P450 (CYP) 3A as novel pharmacoenhancers. Part II: P2/P3 region and discovery of cobicistat (GS-9350) (2013 · Bioorganic & Medicinal Chemistry Letters · 被引 26)
• Correlating Structure and Function of Drug-Metabolizing Enzymes: Progress and Ongoing Challenges (2013 · Drug Metabolism and Disposition · 被引 25)
• Successful Strategies for the Discovery of Antiviral Drugs (2013 · Royal Society of Chemistry eBooks · 被引 24)