Structure–activity relationships of diamine inhibitors of cytochrome P450 (CYP) 3A as novel pharmacoenhancers. Part II: P2/P3 region and discovery of cobicistat (GS-9350)

作者：Lianhong Xu, Hongtao Liu, Allen Y. Hong, Randy Vivian, Bernard P. Murray, Christian Callebaut, You-Chul Choi, Melody S. Lee, Jennifer Chau, Luong Tsai, Kirsten M. Stray, Robert G. Strickley, Jianhong Wang, L. Tong, S. Swaminathan, Gerry Rhodes, Manoj C. Desai · 发表于：Bioorganic & Medicinal Chemistry Letters · 年份：2013 · DOI：10.1016/j.bmcl.2013.12.057 · 被引用次数：26 · 研究领域：Pharmacogenetics and Drug Metabolism、HIV/AIDS drug development and treatment、Pharmacological Effects and Toxicity Studies