Geneviève Laflamme

机构：Héma-Québec

发表论文 42 篇 · 总被引 755 次 · h-index 14

代表论文

• Design and Profiling of GS-9148, a Novel Nucleotide Analog Active against Nucleoside-Resistant Variants of Human Immunodeficiency Virus Type 1, and Its Orally Bioavailable Phosphonoamidate Prodrug, GS-9131 (2007 · Antimicrobial Agents and Chemotherapy · 被引 94)
• Discovery of GS-9131: Design, synthesis and optimization of amidate prodrugs of the novel nucleoside phosphonate HIV reverse transcriptase (RT) inhibitor GS-9148 (2010 · Bioorganic & Medicinal Chemistry · 被引 59)
• Design, synthesis, and anti-HIV activity of 4′-modified carbocyclic nucleoside phosphonate reverse transcriptase inhibitors (2008 · Bioorganic & Medicinal Chemistry · 被引 56)
• Novel Nucleotide Human Immunodeficiency Virus Reverse Transcriptase Inhibitor GS-9148 with a Low Nephrotoxic Potential: Characterization of Renal Transport and Accumulation (2008 · Antimicrobial Agents and Chemotherapy · 被引 55)
• Synthesis of Ester Prodrugs of 9-( S )-[3-Hydroxy-2-(phosphonomethoxy)propyl]-2,6-diaminopurine (HPMPDAP) as Anti-Poxvirus Agents (2010 · Journal of Medicinal Chemistry · 被引 32)
• Validated Reference Panel from Renewable Source of Genomic DNA Available for Standardization of Blood Group Genotyping (2019 · Journal of Molecular Diagnostics · 被引 13)