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Correction to “Discovery and Structure-Based Design of Potent Covalent PPARγ Inverse-Agonists BAY-4931 and BAY-0069”

作者:Douglas L. Orsi, E. Pook, Nico Bräuer, A. Friberg, P. Lienau, C. Lemke, Timo Stellfeld, Ulf Brüggemeier, Vera Pütter, Hanna Meyer, Maria B. Baco, Stephanie Tang, A. Cherniack, Lindsay C. Westlake, Samantha A Bender, M. Kocak, C. Strathdee, M. Meyerson, K. Eis, Jonathan T. Goldstein · 发表于:Journal of Medicinal Chemistry · 年份:2022 · DOI:10.1021/acs.jmedchem.2c02002 · 被引用次数:4 · 研究领域:Medicine

T incorrect PDF file was provided as Supporting Information with the published article. The correct file for this paper is provided here. ■ ASSOCIATED CONTENT *sı Supporting Information The Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c02002. Methods for RNA sequencing and the PRISM multiplexed cell line panel, summary of the HTS screen, PRISM profiling, colony formation assay, RNA sequencing analysis, X-ray structural comparison of the binding modes of BAY-4931 and T0070907, pharmacodynamic analysis of tumors treated with compounds, HPLC traces of in vivo compounds, and NOESY profiles of compounds 8b and 8c (PDF)