C. Lemke

发表论文 51 篇 · 总被引 1094 次 · h-index 19

代表论文

• Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers (2021 · Nature Genetics · 被引 130)
• Discovery of Novel Small-Molecule HIV-1 Replication Inhibitors That Stabilize Capsid Complexes (2013 · Antimicrobial Agents and Chemotherapy · 被引 105)
• Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase (2021 · Nature Communications · 被引 76)
• Structure-function analysis of the SHOC2-MRAS-PP1C holophosphatase complex (2022 · Nature · 被引 63)
• Novel inhibitor binding site discovery on HIV-1 capsid N-terminal domain by NMR and X-ray crystallography. (2013 · ACS Chemical Biology · 被引 44)
• Ligand bioactive conformation plays a critical role in the design of drugs that target the hepatitis C virus NS3 protease. (2014 · Journal of Medicinal Chemistry · 被引 39)