Douglas L. Orsi

发表论文 21 篇 · 总被引 353 次 · h-index 10

代表论文

• Bioorthogonal prodrug activation driven by a strain-promoted 1,3-dipolar cycloaddition (2014 · Chemical Science · 被引 81)
• Fluorination Enables a Ligand-Controlled Regiodivergent Palladium-Catalyzed Decarboxylative Allylation Reaction to Access α,α-Difluoroketones (2015 · Angewandte Chemie · 被引 68)
• Base Catalysis Enables Access to α,α-Difluoroalkylthioethers (2017 · Organic Letters · 被引 54)
• Exploiting the unusual effects of fluorine in methodology. (2017 · Chemical Communications · 被引 43)
• Development of VU6019650: A Potent, Highly Selective, and Systemically Active Orthosteric Antagonist of the M5 Muscarinic Acetylcholine Receptor for the Treatment of Opioid Use Disorder. (2022 · Journal of Medicinal Chemistry · 被引 17)
• Acid-Catalyzed Hydrothiolation of gem-Difluorostyrenes to Access α,α–Difluoroalkylthioethers (2021 · Journal of Organic Chemistry · 被引 16)