The combined effect of commercial tilapia collagen peptides and antioxidants against UV-induced skin photoaging in mice

作者：Bo Song, Dasong Liu, Tristan C. Liu, Kexin Li, S. H. Wang, Jianguo Liu, Joe M. Regenstein, Yuxuan Wu, Peng Zhou · 发表于：Food & Function · 年份：2023 · DOI：10.1039/d3fo01516e · 被引用次数：22 · 研究领域：Skin Protection and Aging、Olfactory and Sensory Function Studies、Dyeing and Modifying Textile Fibers

< 0.05) reduced a* of mouse skin and increased the content of Hyp and type I collagen to varying degrees, thereby improving skin integrity. Furthermore, the combination of CP, HPE, and VCE showed increased upregulation of antioxidant enzyme expression, reduced serum ROS, and decreased inhibition of metalloproteinase expression compared to the other treatment groups. Thus, this combination showed better effects in inhibiting collagen degradation and maintaining the redox balance. The Nrf2/ARE and TGF-β/Smad transcription systems are likely involved in these effects. Therefore, the results suggest that a diet containing CP, astaxanthin, and vitamins might be recommended to improve skin health and appearance.