Meganuclease targeting of PCSK9 in macaque liver leads to stable reduction in serum cholesterol

作者：Lili Wang, Jeff Smith, Camilo Ayala Breton, Peter Clark, Jia Zhang, Ying Lei, Yan Che, Janel Lape, Peter L. Bell, Roberto Calcedo, Elizabeth L. Buza, A. Saveliev, Victor V. Bartsevich, Zhenning He, John Wesley White, Mingyao Li, Derek Jantz, James M. Wilson · 发表于：Nature Biotechnology · 年份：2018 · DOI：10.1038/nbt.4182 · 被引用次数：127 · 研究领域：CRISPR and Genetic Engineering、Viral Infections and Immunology Research、RNA and protein synthesis mechanisms