A G Protein-Biased Ligand at the μ-Opioid Receptor Is Potently Analgesic with Reduced Gastrointestinal and Respiratory Dysfunction Compared with Morphine

作者：Scott M. DeWire, Dennis S. Yamashita, David H. Rominger, Guodong Liu, Conrad L. Cowan, Thomas M. Graczyk, Xiaotao Chen, Philip M. Pitis, Dimitar B. Gotchev, Catherine C.-K. Yuan, Michael Koblish, Michael W. Lark, Jonathan D. Violin · 发表于：Journal of Pharmacology and Experimental Therapeutics · 年份：2013 · DOI：10.1124/jpet.112.201616 · 被引用次数：668 · 研究领域：Receptor Mechanisms and Signaling、Neuropeptides and Animal Physiology、Pharmacological Receptor Mechanisms and Effects