Bruce D. Dorsey
ORCID：0000-0002-2130-9969
发表论文 121 篇 · 总被引 4341 次 · h-index 33
代表论文
- Checkpoint inhibition through small molecule-induced internalization of programmed death-ligand 1 (2021 · Nature Communications · 被引 137)
- Host Poly(A) Polymerases PAPD5 and PAPD7 Provide Two Layers of Protection That Ensure the Integrity and Stability of Hepatitis B Virus RNA (2021 · Journal of Virology · 被引 24)
- Preclinical characterization of AB-506, an inhibitor of HBV replication targeting the viral core protein (2021 · Antiviral Research · 被引 20)
- Rational Design, Synthesis, and Structure–Activity Relationship of a Novel Isoquinolinone-Based Series of HBV Capsid Assembly Modulators Leading to the Identification of Clinical Candidate AB-836 (2024 · Journal of Medicinal Chemistry · 被引 13)
- Structure–Activity Relationships and Discovery of ( S )-6-Isopropyl-2-methoxy-3-(3-methoxypropoxy)-10-oxo-5,10-dihydro-6 H -pyrido[1,2- h ][1,7]naphthyridine-9-carboxylic Acid (AB-452), a Novel Orally Available HBV RNA Destabilizer (2024 · Journal of Medicinal Chemistry · 被引 13)
- Design, synthesis, and structure-activity relationship of a bicyclic HBV capsid assembly modulator chemotype leading to the identification of clinical candidate AB-506 (2023 · Bioorganic & Medicinal Chemistry Letters · 被引 9)