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Design, synthesis, and structure-activity relationship of a bicyclic HBV capsid assembly modulator chemotype leading to the identification of clinical candidate AB-506

作者:Andrew G. Cole, Steven G. Kultgen, Nagraj Mani, Jorge G. Quintero, Kristi Fan, Andrzej Ardzinski, Kim Stever, Bruce D. Dorsey, Janet R. Phelps, Amy C. H. Lee, Emily P. Thi, Tim Chiu, Sunny Tang, P.S. Horanyi, Stephen J. Mayclin, Troy O. Harasym, Michael J. Sofia · 发表于:Bioorganic & Medicinal Chemistry Letters · 年份:2023 · DOI:10.1016/j.bmcl.2023.129456 · 被引用次数:9 · 研究领域:Hepatitis B Virus Studies、Hepatitis C virus research、HIV/AIDS drug development and treatment