Barbra Pagarigan

机构：Bristol-Myers Squibb (Germany), Bristol-Myers Squibb (United States), Bristol-Myers Squibb (United Kingdom), Bristol-Myers Squibb (Belgium)

发表论文 25 篇 · 总被引 2093 次 · h-index 11

代表论文

• A novel cereblon modulator recruits GSPT1 to the CRL4CRBN ubiquitin ligase (2016 · Nature · 被引 702)
• Structure of the human Cereblon–DDB1–lenalidomide complex reveals basis for responsiveness to thalidomide analogs (2014 · Nature Structural & Molecular Biology · 被引 531)
• A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos (2017 · Journal of Medicinal Chemistry · 被引 307)
• Structural analysis of a set of proteins resulting from a bacterial genomics project (2005 · Proteins Structure Function and Bioinformatics · 被引 253)
• Crystal structure of the SALL4–pomalidomide–cereblon–DDB1 complex (2020 · Nature Structural & Molecular Biology · 被引 106)
• The Discovery of a Dual TTK Protein Kinase/CDC2-Like Kinase (CLK2) Inhibitor for the Treatment of Triple Negative Breast Cancer Initiated from a Phenotypic Screen (2017 · Journal of Medicinal Chemistry · 被引 61)