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Structure of the human Cereblon–DDB1–lenalidomide complex reveals basis for responsiveness to thalidomide analogs

作者:Philip P. Chamberlain, Antonia Lopez‐Girona, Karen Miller, Gilles Carmel, Barbra Pagarigan, Barbara Chie-Leon, Emily Rychak, Laura G. Corral, Yan Ren, Maria Wang, Mariko Riley, Silvia L. Delker, Takumi Ito, Hideki Ando, Tomoyuki Mori, Yoshinori Hirano, Hiroshi Handa, Toshio Hakoshima, Thomas O. Daniel, Brian E. Cathers · 发表于:Nature Structural & Molecular Biology · 年份:2014 · DOI:10.1038/nsmb.2874 · 被引用次数:527 · 研究领域:Protein Degradation and Inhibitors、Multiple Myeloma Research and Treatments、Ubiquitin and proteasome pathways