A novel cereblon modulator recruits GSPT1 to the CRL4CRBN ubiquitin ligase

作者：Mary E. Matyskiela, Gang Lu, Takumi Ito, Barbra Pagarigan, Chin-Chun Lu, Karen Miller, Wei Fang, Nai-Yu Wang, Derek Nguyen, Jack Houston, Gilles Carmel, Tam Tran, Mariko Riley, Lyn’Al Nosaka, Gabriel C. Lander, Svetlana Gaidarova, Shuichan Xu, Alexander L. Ruchelman, Hiroshi Handa, James Carmichael, Thomas O. Daniel, Brian E. Cathers, Antonia Lopez‐Girona, Philip P. Chamberlain · 发表于：Nature · 年份：2016 · DOI：10.1038/nature18611 · 被引用次数：702 · 研究领域：Protein Degradation and Inhibitors、Multiple Myeloma Research and Treatments、Ubiquitin and proteasome pathways