Oral Administration of Clostridium butyricum Alleviates High-Fat Diet-Induced Obesity in Mice by Modulating Gut Akkermansia muciniphila Abundance via Direct Growth Promotion

作者：Xinrui Dong, Lin Li, Li Liu, Long Chen, Nan Shang, Ran Wang, Ming Zhang, Hao Zhang, Yanling Hao, Zhengyuan Zhai, Liang Zhao · 发表于：Journal of Microbiology and Biotechnology · 年份：2025 · DOI：10.4014/jmb.2509.09005 · 被引用次数：2 · 研究领域：Gut microbiota and health、Probiotics and Fermented Foods、Immune cells in cancer

(AKK), indicating microbial cross-feeding. These findings demonstrate CLB alleviates obesity by restoring the abundance of AKK, partly through the production of metabolites that promote the proliferation of AKK, offering novel insights into probiotic-driven microbiota modulation for metabolic health.