Towards Accurate and Automated TMS Coil Placement with a Robotic System in MRI: A preliminary study

作者：Alfredo De Goyeneche, Naichen Zhao, Charles Paxson, Binghan He, Ronald S. Fearing, Stella X. Yu, Chunlei Liu, Michael Lustig · 发表于：Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition · 年份：2025 · DOI：10.58530/2025/3310 · 研究领域：Nuclear Materials and Properties、Soft Robotics and Applications、Advanced ceramic materials synthesis

Motivation: Precise TMS control within MRI is fundamental for clinical and neuroscience advancements. However, challenges remain in accurate targeting, variability in functional anatomy, and real-time brain dynamics. Goal(s): We aim to develop a robotic system for accurate, automated TMS coil placement inside MRI. Approach: We developed a 3DOF robotic system to place a mock TMS coil within the MRI environment. Wireless markers identify the end effector's position through fast projection acquisitions, enabling closed-loop adjustments for accurate positioning. Results: We showcase our robotic and localization system working within the MRI environment, detailing the placement precision achieved during initial trials. Impact: This system demonstrates capacity for precise, automated TMS coil positioning within the MRI, laying a foundation for fully integrated TMS-MRI setups. This approach will facilitate patient-specific, adaptive stimulation, enabling studies on dynamic brain-state-driven stimulation and improving clinical reproducibility.