Discovery of the first-in-class DOT1L PROTAC degrader

作者：Hyerin Yim, Renhong Sun, Zhongli Xu, Huen Suk Kim, Min Jeong Kim, Tao Cao, Ling Xie, Xian Chen, H. Ümit Kanıskan, Jian Jin · 发表于：European Journal of Medicinal Chemistry · 年份：2025 · DOI：10.1016/j.ejmech.2025.117595 · 被引用次数：11 · 研究领域：Protein Degradation and Inhibitors、Ubiquitin and proteasome pathways、Peptidase Inhibition and Analysis