Ultrasound-mediated nanomaterials for the treatment of inflammatory diseases

作者：Kai Zhang, Tingting Wang, Xingyong Huang, Peng Wu, Lufan Shen, Yuanyuan Yang, Wenyu Wan, Siyu Sun, Zhan Zhang · 发表于：Ultrasonics Sonochemistry · 年份：2025 · DOI：10.1016/j.ultsonch.2025.107270 · 被引用次数：7 · 研究领域：Ultrasound and Hyperthermia Applications、Medical and Biological Ozone Research、Photoacoustic and Ultrasonic Imaging

The mechanisms by which ultrasound enhances nanomaterial effects include enhancing the delivery of nanomaterials, controlling drug release, and playing a role in SDT. Ultrasound-mediated nanomaterials can treat a wide range of infection-associated and sterile inflammatory diseases. Future development should focus on material refinement, instrumentation standardization, exploring new mechanisms of action, and expanding the field of therapeutic diseases. • The mechanisms by which ultrasound enhances nanomaterial effects include enhancing the delivery of nanomaterials, controlling drug release, and playing a role in SDT. • Ultrasound-mediated nanomaterials can treat a wide range of infection-associated and sterile inflammatory diseases. • Future development should focus on material refinement, instrumentation standardization, exploring new mechanisms of action, and expanding the field of therapeutic diseases. Sterile and infection-associated inflammatory diseases are becoming increasingly prevalent worldwide. Conventional drug therapies often entail significant drawbacks, such as the risk of drug overdose, the development of drug resistance in pathogens, and systemic adverse reactions, all of which can undermine the effectiveness of treatments for these conditions. Nanomaterials (NMs) have emerged as a promising tool in the treatment of inflammatory diseases due to their precise targeting capabilities, tunable characteristics, and responsiveness to external stimuli. Ultrasound (...