A switchable magnetic resonance imaging nanoplatform for in situ microRNA imaging

作者：Yan Tan, Junren Wang, Qian Wan, Jinlong Yang, Jinkun Huang, Zijia Zhou, Haifeng Dong, Xueji Zhang · 发表于：Chemical Science · 年份：2024 · DOI：10.1039/d4sc04675g · 被引用次数：6 · 研究领域：Advanced biosensing and bioanalysis techniques、Nanoplatforms for cancer theranostics、Extracellular vesicles in disease

A “large-small-large” size-switchable PAA-Fe 3 O 4 -DNA@PPP nanoplatform maintains a large size in the circulation system and discomposites into small-size in the TME condition and finally assembles into larger-size by miRNA.