IL-10-expressing CAR T cells resist dysfunction and mediate durable clearance of solid tumors and metastases

作者：Yang Zhao, Jiangqing Chen, Massimo Andreatta, Bing Feng, Yuqing Xie, Mathias Wenes, Yi Wang, Min Gao, Xiaomeng Hu, Pedro Romero, Santiago J. Carmona, Jie Sun, Yugang Guo, Li Tang · 发表于：Nature Biotechnology · 年份：2024 · DOI：10.1038/s41587-023-02060-8 · 被引用次数：298 · 研究领域：CAR-T cell therapy research、Immune Cell Function and Interaction、T-cell and B-cell Immunology