Jiangqing Chen

机构：Gannan Medical University, First Affiliated Hospital Zhejiang University, Zhejiang University

发表论文 15 篇 · 总被引 550 次 · h-index 8

代表论文

• IL-10-expressing CAR T cells resist dysfunction and mediate durable clearance of solid tumors and metastases (2024 · Nature Biotechnology · 被引 285)
• Tuning the ignition of CAR: optimizing the affinity of scFv to improve CAR-T therapy (2021 · Cellular and Molecular Life Sciences · 被引 108)
• Cas9‐Cleavage Sequences in Size‐Reduced Plasmids Enhance Nonviral Genome Targeting of CARs in Primary Human T Cells (2021 · Small Methods · 被引 33)
• CD38‐Specific CAR Integrated into CD38 Locus Driven by Different Promoters Causes Distinct Antitumor Activities of T and NK Cells (2023 · Advanced Science · 被引 29)
• Inserting EF1α-driven CD7-specific CAR at CD7 locus reduces fratricide and enhances tumor rejection (2023 · Leukemia · 被引 26)
• Balancing activation and co-stimulation of CAR tunes signaling dynamics and enhances therapeutic potency (2022 · Molecular Therapy · 被引 18)