Global trends in research of mitophagy in liver diseases over past two decades: A bibliometric analysis

作者：Jie Lin, Yushun Chang, Meiling Hu, Qiuxia Gu, Jinyao Dai, Junjie Nan, Ziyuan Wang, Jiachen Chen, Danyang Zhong, Enjie Zhou, Yifan Wang, Xiujun Cai · 发表于：Heliyon · 年份：2023 · DOI：10.1016/j.heliyon.2023.e18843 · 被引用次数：9 · 研究领域：Autophagy in Disease and Therapy、Inflammasome and immune disorders、Ginger and Zingiberaceae research

Increasing evidence indicated that mitophagy might play a crucial role in the occurrence and progression of liver diseases. In order to enhance our understanding of the intricate relationship between mitophagy and liver diseases, a comprehensive bibliometric analysis of the existing literature in this field was conducted. This analysis aimed to identify key trends, potential areas of future research, and forecast the development of this specific field. We systematically searched the Web of Science Core Collection (WoSCC) for publications related to mitophagy in liver diseases from 2000 to 2022. We conducted the bibliometric analysis and data visualization through VOSviewer and CiteSpace. The analysis of publication growth revealed a substantial increase in articles published in this field over the past years, indicating mitophagy's growing interest and significance in liver diseases. China and USA emerged as the leading contributors in the number of papers, with 294 and 194 independent papers, respectively. Exploring the mechanism of mitophagy in the initiation and procession of liver diseases was the main content of studies in this field, and Parkin-independent mediated mitophagy has attracted much attention recently. "Lipid metabolism," "cell death," "liver fibrosis" and "oxidative stress" were the primary keywords clusters. Additionally, "nlrp3 inflammasome", "toxicity" and "nonalcoholic steatohepatitis" were emerging research hotspots in this area and have the potential t...