Potent and uniform fetal hemoglobin induction via base editing

作者：Thiyagaraj Mayuranathan, Gregory A. Newby, Ruopeng Feng, Yu Yao, Kalin D. Mayberry, Cícera Regina Lazzarotto, Yichao Li, Rachel M. Levine, Nikitha Nimmagadda, Erin Dempsey, Guolian Kang, Shaina N. Porter, Phillip A. Doerfler, Jingjing Zhang, Yoonjeong Jang, Jingjing Chen, Henry William Bell, Merlin Crossley, Senthil Velan Bhoopalan, Akshay Sharma, John F. Tisdale, Shondra M. Pruett‐Miller, Yong Cheng, Shengdar Q. Tsai, David R. Liu, Mitchell J. Weiss, Jonathan S. Yen · 发表于：Nature Genetics · 年份：2023 · DOI：10.1038/s41588-023-01434-7 · 被引用次数：80 · 研究领域：Hemoglobinopathies and Related Disorders、Prenatal Screening and Diagnostics、Neonatal Health and Biochemistry