Jonathan S. Yen

机构：St. Jude Children's Research Hospital · ORCID：0000-0002-9432-9450

发表论文 59 篇 · 总被引 3122 次 · h-index 22

代表论文

• Directed evolution of adenine base editors with increased activity and therapeutic application (2020 · Nature Biotechnology · 被引 551)
• Base editing of haematopoietic stem cells rescues sickle cell disease in mice (2021 · Nature · 被引 395)
• Selective in vivo metabolic cell-labeling-mediated cancer targeting (2017 · Nature Chemical Biology · 被引 385)
• Ex vivo prime editing of patient haematopoietic stem cells rescues sickle-cell disease phenotypes after engraftment in mice (2023 · Nature Biomedical Engineering · 被引 156)
• Bone-marrow-homing lipid nanoparticles for genome editing in diseased and malignant haematopoietic stem cells (2024 · Nature Nanotechnology · 被引 127)
• Potent and uniform fetal hemoglobin induction via base editing (2023 · Nature Genetics · 被引 81)