Effects of particle size reduction combined with β-cyclodextrin on the in vitro dissolution and in vivo relative bioavailability of ginsenosides in Panax ginseng

作者：Chang Liu, Tao Yang, Zikuan Zhao, Tristan C. Liu, Kexin Li, Jianguo Liu, Peng Zhou · 发表于：Food & Function · 年份：2022 · DOI：10.1039/d2fo01098d · 被引用次数：14 · 研究领域：Ginseng Biological Effects and Applications、Pharmacological Effects of Natural Compounds、Phytoestrogen effects and research

experiments; in contrast, the deglycosylation states of PPT-type ginsenosides varied, which might be attributed to the relatively low abundance, glycosylation linkage, and potential involvement of the gut microbiota metabolism. Conclusively, ultrafine milling combined with a dispersant provides a simple and scalable manufacturing process that can effectively improve the bioavailability of ginseng products.