Diverse alterations associated with resistance to KRAS(G12C) inhibition

作者：Yulei Zhao, Yonina R. Murciano‐Goroff, Jenny Y. Xue, Agnes Ang, Jessica Lucas, Trang T. Mai, Arnaud Da Cruz Paula, Anne Y. Saiki, Deanna Mohn, Pragathi Achanta, Ann Elizabeth Sisk, Kanika Arora, Rohan S. Roy, Dong-Sung Kim, Chuanchuan Li, Lee P. Lim, Mark Li, Amber Bahr, Brian Houck‐Loomis, Elisa de Stanchina, Jorge S. Reis-Filho, Britta Weigelt, Michael F. Berger, Gregory J. Riely, Kathryn C. Arbour, J. Russell Lipford, Bob T. Li, Piro Lito · 发表于：Nature · 年份：2021 · DOI：10.1038/s41586-021-04065-2 · 被引用次数：470 · 研究领域：Protein Kinase Regulation and GTPase Signaling、PI3K/AKT/mTOR signaling in cancer、Lung Cancer Treatments and Mutations