Anne Y. Saiki

机构：Amgen (United States) · ORCID：0000-0003-3913-1860

发表论文 58 篇 · 总被引 5223 次 · h-index 21

代表论文

• Diverse alterations associated with resistance to KRAS(G12C) inhibition (2021 · Nature · 被引 470)
• Identification of Structurally Novel KRAS G12C Inhibitors through Covalent DNA-Encoded Library Screening (2025 · Journal of Medicinal Chemistry · 被引 21)
• LKB1 regulates JNK-dependent stress signaling and apoptotic dependency of KRAS-mutant lung cancers (2025 · Nature Communications · 被引 10)
• Abstract ND01: AMG 410: An H/NRAS-sparing pan-KRAS inhibitor with dual GTP(on)/GDP(off)-state activity for the treatment of diverse KRAS-mutant tumors (2025 · Cancer Research · 被引 7)
• Abstract 5866: Preclinical combination approaches with the pan-KRAS inhibitor AMG 410 in KRAS- mutant cancers (2026 · Cancer Research · 被引 1)
• Abstract 4369: Preclinical characterization of a dual-state pan-KRAS Inhibitor (2025 · Cancer Research · 被引 1)