Foam sclerotherapy for below knee varicosities after great saphenous ligation and stripping

作者：Zuqi Xia, Chen Yao, Runnan Shen, Guochang You, Kai Huang · 发表于：Vascular Investigation and Therapy · 年份：2021 · DOI：10.4103/2589-9686.328157 · 研究领域：Diagnosis and Treatment of Venous Diseases、Venous Thromboembolism Diagnosis and Management、Dermatologic Treatments and Research

AIMS: This study aimed to compare the short-term clinical results of multiple foam sclerosant injection (MFSI) and endovenous foam sclerosant perfusion (EFSP) for treating varicose veins (VV) in the lower extremities through. SUBJECTS AND METHODS: The study included 111 cases. All patients had high saphenous ligation and stripping just before the foam injection. First-stage sclerotherapy effects, sclerosant dosage, postoperative complications, and other clinical assessments were included as observation items with at least 6 months of follow-up. RESULTS: The treatment effects of the 2 VV treatment methods showed no significant difference ( P < 0.05) during primary closure. However, EFSP requires a lower sclerosant dosage, resulting in a lower occurrence of thrombophlebitis than that with MFSI ( P < 0.05). In the follow-up period, no significant difference in recurrence rate was found between the groups ( P > 0.05). Although superficial thrombophlebitis and pigmentation occurred in both groups, the EFSP group appeared to be more prone to remission ( P < 0.05), as there were no vein-puncture injuries or factors to cause local hematoma. Superficial thrombophlebitis and skin pigmentation were less in the EFSP than the MSFI group (4.4% vs. 16%; P = 0.033 and 8.8% vs. 30.2%; P = 0.004, respectively). CONCLUSIONS: Both MFSI and EPSP visibly affect VV in the lower extremities, but when complications and the simplicity and reproducibility of operation techniques are conside...