Safety of central compartment neck dissection for transoral endoscopic thyroid surgery in papillary thyroid carcinoma

作者：Tiantian Wang, Yanping Wu, Qiuping Xie, Haichen Yan, Xiaoming Zhou, Xing Yu, Yufei Chen, Cheng Xiang, Haichao Yan, Qunzi Zhao, Maolin Zhang, Ming Qi, Ping Wang, Yong Wang · 发表于：Japanese Journal of Clinical Oncology · 年份：2019 · DOI：10.1093/jjco/hyz195 · 被引用次数：47 · 研究领域：Thyroid and Parathyroid Surgery、Thyroid Cancer Diagnosis and Treatment、Head and Neck Anomalies

BACKGROUND: Remote access and endoscopic thyroid surgery has been gaining popularity because it allows patients to avoid a visible scar in the neck. There is limited data on transoral endoscopic thyroidectomy when it relates to patients with papillary thyroid carcinoma. We aim to evaluate the safety of ipsilateral central compartment dissection for patients who undergo transoral thyroidectomy (thyroidectomy vestibular approach-compartment lymph node dissection). PATIENTS AND METHODS: A total of 80 patients who underwent thyroidectomy vestibular approach-compartment lymph node dissection for papillary thyroid carcinoma from June 2015 to September 2016 were identified. Over the same period, a matched cohort of 80 patients who underwent open thyroidectomy with routine ipsilateral central compartment dissection was also identified (Open-compartment lymph node dissection). The two groups were analyzed in terms of patient characteristics, perioperative clinical results and post-operative outcomes. RESULTS: All patients were female with a mean age of 32-year. There was no difference in mean maximum tumor size and number of lymph nodes dissected. Moreover, there was no difference in average positive lymph nodes between thyroidectomy vestibular approach-compartment lymph node dissection and Open-compartment lymph node dissection (1.48 vs 1.08, P = 0.647). Operative time was longer in the thyroidectomy vestibular approach-compartment lymph node dissection group (193 vs 102 min, P < 0.0...