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GPR40-Mediated Gα12 Activation by Allosteric Full Agonists Highly Efficacious at Potentiating Glucose-Stimulated Insulin Secretion in Human Islets

作者:M. Rives, Brian Rady, Nadia Swanson, Shuyuan Zhao, Jenson Qi, Éric Arnoult, Ivona Bakaj, Arturo Mancini, Billy Breton, S. Paul Lee, Mark R. Player, Alessandro Pocai · 发表于:Molecular Pharmacology · 年份:2018 · DOI:10.1124/mol.117.111369 · 被引用次数:26 · 研究领域:Diabetes Treatment and Management、Pancreatic function and diabetes、Receptor Mechanisms and Signaling