Brian Rady

机构：Janssen (United States) · ORCID：0000-0001-5217-9354

发表论文 20 篇 · 总被引 353 次 · h-index 10

代表论文

• Persistent or Transient Human β Cell Dysfunction Induced by Metabolic Stress: Specific Signatures and Shared Gene Expression with Type 2 Diabetes (2020 · Cell Reports · 被引 118)
• Phase 1 Trials of PNPLA3 siRNA in I148M Homozygous Patients with MAFLD (2024 · New England Journal of Medicine · 被引 65)
• Overexpression of E2F3 promotes proliferation of functional human β cells without induction of apoptosis (2013 · Cell Cycle · 被引 31)
• GPR40-Mediated Gα12 Activation by Allosteric Full Agonists Highly Efficacious at Potentiating Glucose-Stimulated Insulin Secretion in Human Islets (2018 · Molecular Pharmacology · 被引 26)
• Discovery of a GPR40 Superagonist: The Impact of Aryl Propionic Acid α-Fluorination (2018 · ACS Medicinal Chemistry Letters · 被引 25)
• Discovery of novel potent imidazo[1,2-b]pyridazine PDE10a inhibitors (2016 · Bioorganic & Medicinal Chemistry Letters · 被引 18)