Potential Effects of Desalinated Seawater on Arteriosclerosis in Rats.

作者：Lian Duan, Li Xia Zhang, Shao Ping Zhang, Jian Kong, Zhi Hong, Ming Zhang, Kai Lu, Hong Wei Zhang · 发表于：PubMed · 年份：2017 · DOI：10.3967/bes2017.102 · 研究领域：Magnesium in Health and Disease、Biomarkers in Disease Mechanisms、Hydrogen's biological and therapeutic effects

To evaluate the potential risk of arteriosclerosis caused by desalinated seawater, Wistar rats were provided desalinated seawater over a 1-year period, and blood samples were collected at 0, 90, 180, and 360 days. Blood calcium, magnesium, and arteriosclerosis-related indicators were investigated. Female rats treated with desalinated seawater for 180 days showed lower magnesium levels than the control rats (P < 0.05). The calcium and magnesium levels in female rats and the magnesium level in male rats were lower than the levels in the controls, following treatment with desalinated seawater for 360 days (P < 0.05). Blood levels of arteriosclerosis-related lipid peroxidation indicators and C-reactive protein (CRP) in the treatment group did not differ from those in the controls. The levels of lipid peroxidation indicators and CRP in rats were not significantly affected by drinking desalinated seawater, and no increase in risk of arteriosclerosis was observed.