Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

作者：Brinda Ravikumar, Corinne Vacher, Zdenek Berger, J. Eric Davies, Shouqing Luo, Lourdes Garcia Oroz, Francesco Scaravilli, Douglas F. Easton, Rainer Duden, Cahir J. O’Kane, David Chaim Rubinsztein · 发表于：Nature Genetics · 年份：2004 · DOI：10.1038/ng1362 · 被引用次数：2354 · 研究领域：Genetic Neurodegenerative Diseases、Mitochondrial Function and Pathology、Muscle Physiology and Disorders