J. Eric Davies

机构：University of Cambridge, Addenbrooke's Hospital · ORCID：0000-0002-8853-8328

发表论文 35 篇 · 总被引 6787 次 · h-index 17

代表论文

• Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease (2004 · Nature Genetics · 被引 2356)
• Regulation of Mammalian Autophagy in Physiology and Pathophysiology (2010 · Physiological Reviews · 被引 1748)
• Trehalose, a Novel mTOR-independent Autophagy Enhancer, Accelerates the Clearance of Mutant Huntingtin and α-Synuclein (2006 · Journal of Biological Chemistry · 被引 1144)
• Huntington's disease: from pathology and genetics to potential therapies (2008 · Biochemical Journal · 被引 413)
• Trehalose reduces aggregate formation and delays pathology in a transgenic mouse model of oculopharyngeal muscular dystrophy (2005 · Human Molecular Genetics · 被引 206)
• Cdk5 phosphorylation of huntingtin reduces its cleavage by caspases (2005 · The Journal of Cell Biology · 被引 195)