Thioredoxin-1 binds to the C2 domain of PTEN inhibiting PTEN's lipid phosphatase activity and membrane binding: a mechanism for the functional loss of PTEN's tumor suppressor activity

作者：Emmanuelle J. Meuillet, Daruka Mahadevan, Margareta I. Berggren, Amy Coon, Garth Powis · 发表于：Archives of Biochemistry and Biophysics · 年份：2004 · DOI：10.1016/j.abb.2004.04.020 · 被引用次数：193 · 研究领域：PI3K/AKT/mTOR signaling in cancer、Redox biology and oxidative stress、Enzyme function and inhibition