Margareta I. Berggren

机构：Linköping University

发表论文 46 篇 · 总被引 2929 次 · h-index 26

代表论文

• Molecular pharmacology and antitumor activity of PX-866, a novel inhibitor of phosphoinositide-3-kinase signaling (2004 · Molecular Cancer Therapeutics · 被引 313)
• Thioredoxin and thioredoxin reductase gene expression in human tumors and cell lines, and the effects of serum stimulation and hypoxia. (1997 · PubMed · 被引 309)
• 3-(Hydroxymethyl)-Bearing Phosphatidylinositol Ether Lipid Analogues and Carbonate Surrogates Block PI3-K, Akt, and Cancer Cell Growth (2000 · Journal of Medicinal Chemistry · 被引 195)
• Thioredoxin-1 binds to the C2 domain of PTEN inhibiting PTEN's lipid phosphatase activity and membrane binding: a mechanism for the functional loss of PTEN's tumor suppressor activity (2004 · Archives of Biochemistry and Biophysics · 被引 193)
• Transfection with human thioredoxin increases cell proliferation and a dominant-negative mutant thioredoxin reverses the transformed phenotype of human breast cancer cells. (1996 · PubMed · 被引 162)
• The phosphatidylinositol-3-kinase inhibitor PX-866 overcomes resistance to the epidermal growth factor receptor inhibitor gefitinib in A-549 human non–small cell lung cancer xenografts (2005 · Molecular Cancer Therapeutics · 被引 152)