Zheng‐Yi Chen

机构：Massachusetts Eye and Ear Infirmary, Harvard University · ORCID：0000-0002-1452-4193

发表论文 97 篇 · 总被引 6636 次 · h-index 37

代表论文

• AAV1-hOTOF gene therapy for autosomal recessive deafness 9: a single-arm trial (2024 · The Lancet · 被引 352)
• Bilateral gene therapy in children with autosomal recessive deafness 9: single-arm trial results (2024 · Nature Medicine · 被引 138)
• Treatment of monogenic and digenic dominant genetic hearing loss by CRISPR-Cas9 ribonucleoprotein delivery in vivo (2023 · Nature Communications · 被引 49)
• Targeted genome editing restores auditory function in adult mice with progressive hearing loss caused by a human microRNA mutation (2024 · Science Translational Medicine · 被引 29)
• Gene Therapy vs Cochlear Implantation in Restoring Hearing Function and Speech Perception for Individuals With Congenital Deafness (2025 · JAMA Neurology · 被引 19)
• Multicentre gene therapy for OTOF-related deafness followed up to 2.5 years (2026 · Nature · 被引 15)