Jaclyn L. Henderson

机构：Jnana Therapeutics (United States) · ORCID：0000-0002-7097-1350

发表论文 32 篇 · 总被引 1375 次 · h-index 15

代表论文

• Palladium-catalyzed coupling of functionalized primary and secondary amines with aryl and heteroaryl halides: two ligands suffice in most cases (2010 · Chemical Science · 被引 360)
• Mechanism-Based Inactivation (MBI) of Cytochrome P450 Enzymes: Structure–Activity Relationships and Discovery Strategies To Mitigate Drug–Drug Interaction Risks (2012 · Journal of Medicinal Chemistry · 被引 220)
• Discovery and Preclinical Profiling of 3-[4-(Morpholin-4-yl)-7 H -pyrrolo[2,3- d ]pyrimidin-5-yl]benzonitrile (PF-06447475), a Highly Potent, Selective, Brain Penetrant, and in Vivo Active LRRK2 Kinase Inhibitor (2014 · Journal of Medicinal Chemistry · 被引 185)
• Efficient Pd-Catalyzed Amination Reactions for Heterocycle Functionalization (2010 · Organic Letters · 被引 67)
• Palladium-Catalyzed Amination of Unprotected Halo-7-azaindoles (2010 · Organic Letters · 被引 61)
• Palladium-Catalyzed N-Arylation of 2-Aminothiazoles (2012 · Organic Letters · 被引 58)