Jennifer Kahler

机构：Pfizer (United States) · ORCID：0000-0002-4088-0888

发表论文 42 篇 · 总被引 876 次 · h-index 9

代表论文

• Kinetic Analysis of Epidermal Growth Factor Receptor Somatic Mutant Proteins Shows Increased Sensitivity to the Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, Erlotinib (2006 · Cancer Research · 被引 448)
• Preclinical Characterization of OSI-027, a Potent and Selective Inhibitor of mTORC1 and mTORC2: Distinct from Rapamycin (2011 · Molecular Cancer Therapeutics · 被引 203)
• OSI-930: A Novel Selective Inhibitor of Kit and Kinase Insert Domain Receptor Tyrosine Kinases with Antitumor Activity in Mouse Xenograft Models (2006 · Cancer Research · 被引 83)
• Discovery of 7-aminofuro[2,3-c]pyridine inhibitors of TAK1: Optimization of kinase selectivity and pharmacokinetics (2013 · Bioorganic & Medicinal Chemistry Letters · 被引 26)
• Enhanced Antitumor Activity of an Anti-5T4 Antibody–Drug Conjugate in Combination with PI3K/mTOR inhibitors or Taxanes (2015 · Clinical Cancer Research · 被引 25)
• Development of Highly Optimized Antibody–Drug Conjugates against CD33 and CD123 for Acute Myeloid Leukemia (2020 · Clinical Cancer Research · 被引 23)