Becky K.C. Chan

机构：State Key Laboratory of Synthetic Chemistry, University of Hong Kong · ORCID：0000-0003-0121-2788

发表论文 25 篇 · 总被引 201 次 · h-index 5

代表论文

• Combinatorial mutagenesis en masse optimizes the genome editing activities of SpCas9 (2019 · Nature Methods · 被引 64)
• A Three-Way Combinatorial CRISPR Screen for Analyzing Interactions among Druggable Targets (2020 · Cell Reports · 被引 50)
• Machine learning-coupled combinatorial mutagenesis enables resource-efficient engineering of CRISPR-Cas9 genome editor activities (2022 · Nature Communications · 被引 42)
• High-fidelity KKH variant of Staphylococcus aureus Cas9 nucleases with improved base mismatch discrimination (2021 · Nucleic Acids Research · 被引 21)
• A combined enteric neuron-gastric tumor organoid reveals metabolic vulnerabilities in gastric cancer (2025 · Cell stem cell · 被引 17)
• Extensible combinatorial CRISPR screening in mammalian cells (2021 · STAR Protocols · 被引 5)