Christopher A. Vakulskas

机构：Integrated DNA Technologies (United States) · ORCID：0000-0001-8510-4332

发表论文 52 篇 · 总被引 5801 次 · h-index 34

代表论文

• Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases (2022 · Nature Biotechnology · 被引 451)
• Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease (2025 · New England Journal of Medicine · 被引 328)
• AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicines (2021 · Nature Communications · 被引 176)
• Development of β-globin gene correction in human hematopoietic stem cells as a potential durable treatment for sickle cell disease (2021 · Science Translational Medicine · 被引 166)
• Generation of the transgene-free canker-resistant Citrus sinensis using Cas12a/crRNA ribonucleoprotein in the T0 generation (2023 · Nature Communications · 被引 85)
• Gene replacement of α-globin with β-globin restores hemoglobin balance in β-thalassemia-derived hematopoietic stem and progenitor cells (2021 · Nature Medicine · 被引 85)