Wen-Juan Gan

机构：Soochow University, Second Affiliated Hospital of Soochow University, First Affiliated Hospital of Soochow University · ORCID：0000-0002-0436-1028

发表论文 63 篇 · 总被引 1409 次 · h-index 18

代表论文

• Wnt/β-Catenin Signaling Pathway in the Development and Progression of Colorectal Cancer (2023 · Cancer Management and Research · 被引 127)
• Histone lactylation inhibits RARγ expression in macrophages to promote colorectal tumorigenesis through activation of TRAF6-IL-6-STAT3 signaling (2024 · Cell Reports · 被引 118)
• TRIM21 induces selective autophagic degradation of c-Myc and sensitizes regorafenib therapy in colorectal cancer (2024 · Proceedings of the National Academy of Sciences · 被引 45)
• TRIM21 is a druggable target for the treatment of metastatic colorectal cancer through ubiquitination and activation of MST2 (2023 · Cell chemical biology · 被引 38)
• Intrathecal CRISPR-edited allogeneic IL-13Rα2 CAR T Cells for recurrent high-grade Glioma: preclinical characterization and phase I trial (2026 · Nature Communications · 被引 7)
• Extracellular CD44 lactylation impairs CD8+ T cell function in KRAS-mutant colorectal cancer (2026 · Nature Metabolism · 被引 6)