Wayman Chan

机构：Roche (United States)

发表论文 11 篇 · 总被引 311 次 · h-index 9

代表论文

• Mass spectrometry-based multi-attribute method in protein therapeutics product quality monitoring and quality control (2023 · mAbs · 被引 56)
• Selective and Brain‐Permeable Polo‐like Kinase‐2 (Plk‐2) Inhibitors That Reduce α‐Synuclein Phosphorylation in Rat Brain (2013 · ChemMedChem · 被引 51)
• A Comprehensive Assessment of All-Oleate Polysorbate 80: Free Fatty Acid Particle Formation, Interfacial Protection and Oxidative Degradation (2021 · Pharmaceutical Research · 被引 41)
• Physicochemical and biological impact of metal-catalyzed oxidation of IgG1 monoclonal antibodies and antibody-drug conjugates via reactive oxygen species (2022 · mAbs · 被引 33)
• Design and synthesis of brain penetrant selective JNK inhibitors with improved pharmacokinetic properties for the prevention of neurodegeneration (2011 · Bioorganic & Medicinal Chemistry Letters · 被引 33)
• Design and synthesis of highly selective, orally active Polo-like kinase-2 (Plk-2) inhibitors (2013 · Bioorganic & Medicinal Chemistry Letters · 被引 30)