Zedu Huang

机构：Fudan University, Chemical Synthesis Lab · ORCID：0000-0003-3320-3392

发表论文 53 篇 · 总被引 939 次 · h-index 17

代表论文

• Batch and continuous flow asymmetric synthesis of anabolic-androgenic steroids via a single-cell biocatalytic Δ 1 -dehydrogenation and C17β-carbonyl reduction cascade (2023 · Green Chemistry · 被引 27)
• Biocatalytic dynamic reductive kinetic resolution of aryl α-chloro β-keto esters: divergent, stereocontrolled synthesis of diltiazem, clentiazem, and siratiazem (2022 · Chemical Communications · 被引 19)
• Asymmetric synthesis of syn-aryl-(2S,3R)-2-chloro-3-hydroxy esters via an engineered ketoreductase-catalyzed dynamic reductive kinetic resolution (2023 · Chinese Chemical Letters · 被引 17)
• Ene-Reductase-Catalyzed Enantioselective Desymmetrization of Cyclohexadienones: Straightforward Access to All-Carbon Quaternary Stereocenters (2024 · ACS Catalysis · 被引 16)
• Asymmetric Synthesis of Sterically Hindered 1-Substituted Tetrahydro-β-carbolines Enabled by Imine Reductase: Enzyme Discovery, Protein Engineering, and Reaction Development (2023 · Organic Letters · 被引 15)
• Engineered ketoreductase-catalyzed stereoselective reduction of ethyl 2′-ketopantothenate and its analogues: chemoenzymatic synthesis of d -pantothenic acid (2024 · Green Chemistry · 被引 14)