John P. Guilinger

发表论文 31 篇 · 总被引 4788 次 · h-index 15

代表论文

• High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity (2013 · Nature Biotechnology · 被引 1551)
• Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo (2014 · Nature Biotechnology · 被引 1497)
• Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification (2014 · Nature Biotechnology · 被引 855)
• Broad specificity profiling of TALENs results in engineered nucleases with improved DNA-cleavage specificity (2014 · Nature Methods · 被引 217)
• Machine Learning on DNA-Encoded Libraries: A New Paradigm for Hit Finding (2020 · Journal of Medicinal Chemistry · 被引 167)
• Continuous directed evolution of DNA-binding proteins to improve TALEN specificity (2015 · Nature Methods · 被引 127)