Tom Owen‐Hughes

机构：University of Dundee · ORCID：0000-0002-0618-8185

发表论文 147 篇 · 总被引 13367 次 · h-index 57

代表论文

• BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design (2019 · Nature Chemical Biology · 被引 589)
• Histone degradation in response to DNA damage enhances chromatin dynamics and recombination rates (2017 · Nature Structural & Molecular Biology · 被引 275)
• Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome (2018 · eLife · 被引 113)
• Efficient analysis of mammalian polysomes in cells and tissues using Ribo Mega-SEC (2018 · eLife · 被引 78)
• Structural reorganization of the chromatin remodeling enzyme Chd1 upon engagement with nucleosomes (2017 · eLife · 被引 66)
• Acute depletion of the ARID1A subunit of SWI/SNF complexes reveals distinct pathways for activation and repression of transcription (2021 · Cell Reports · 被引 56)