Ryan R. Willard

ORCID：0009-0009-0048-6999

发表论文 41 篇 · 总被引 2718 次 · h-index 13

代表论文

• Catalytic in vivo protein knockdown by small-molecule PROTACs (2015 · Nature Chemical Biology · 被引 1367)
• Androgen receptor degradation by the proteolysis-targeting chimera ARCC-4 outperforms enzalutamide in cellular models of prostate cancer drug resistance (2018 · Communications Biology · 被引 354)
• ARV-110: An oral androgen receptor PROTAC degrader for prostate cancer. (2019 · Journal of Clinical Oncology · 被引 215)
• Oral Estrogen Receptor PROTAC Vepdegestrant (ARV-471) Is Highly Efficacious as Monotherapy and in Combination with CDK4/6 or PI3K/mTOR Pathway Inhibitors in Preclinical ER+ Breast Cancer Models (2024 · Clinical Cancer Research · 被引 193)
• Abstract P5-04-18: ARV-471, an oral estrogen receptor PROTAC degrader for breast cancer (2019 · Cancer Research · 被引 135)
• Abstract 44: The discovery of ARV-471, an orally bioavailable estrogen receptor degrading PROTAC for the treatment of patients with breast cancer (2021 · Cancer Research · 被引 116)